Bacillus anthracis: Balancing innocent research with dual-use potential
Identifieur interne : 000230 ( France/Analysis ); précédent : 000229; suivant : 000231Bacillus anthracis: Balancing innocent research with dual-use potential
Auteurs : Michael J. Hudson [Royaume-Uni] ; Wolfgang Beyer [Allemagne] ; Reinhard Böhm [Allemagne] ; Antonio Fasanella [Italie] ; Giuliano Garofolo [Italie] ; Robert Golinski [Allemagne] ; Pierre L. Goossens [France] ; Ulrike Hahn [Allemagne] ; Bassam Hallis [Royaume-Uni] ; Annemarie King [Royaume-Uni] ; Michèle Mock [France] ; Cesare Montecucco [Italie] ; Amanda Ozin [Allemagne] ; Fiorella Tonello [Italie] ; Stefan H. E. Kaufmann [Allemagne]Source :
- International Journal of Medical Microbiology [ 1438-4221 ] ; 2008.
Abstract
Anthrax Euronet, a Coordination Action of the EU 6th Framework Programme, was designed to strengthen networking activities between anthrax research groups in Europe and to harmonise protocols for testing anthrax vaccines and therapeutics. Inevitably, the project also addressed aspects of the current political issues of biosecurity and dual-use research, i.e. research into agents of important diseases of man, livestock or agriculture that could be used as agents of bioterrorism. This review provides a comprehensive overview of the biology of
Url:
DOI: 10.1016/j.ijmm.2007.09.007
PubMed: 18375178
PubMed Central: 7106442
Affiliations:
- Allemagne, France, Italie, Royaume-Uni
- Bade-Wurtemberg, Berlin, District de Stuttgart, Île-de-France
- Berlin, Paris, Stuttgart
- Université de Hohenheim
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PMC:7106442Le document en format XML
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Hudson</name><affiliation wicri:level="1"><nlm:aff id="aff1">Health Protection Agency, Porton Down, Salisbury, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Health Protection Agency, Porton Down, Salisbury</wicri:regionArea><wicri:noRegion>Salisbury</wicri:noRegion></affiliation></author><author><name sortKey="Beyer, Wolfgang" sort="Beyer, Wolfgang" uniqKey="Beyer W" first="Wolfgang" last="Beyer">Wolfgang Beyer</name><affiliation wicri:level="4"><nlm:aff id="aff2">University of Hohenheim, Stuttgart, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>University of Hohenheim, Stuttgart</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Stuttgart</region><settlement type="city">Stuttgart</settlement></placeName><orgName type="university">Université de Hohenheim</orgName></affiliation></author><author><name sortKey="Bohm, Reinhard" sort="Bohm, Reinhard" uniqKey="Bohm R" first="Reinhard" last="Böhm">Reinhard Böhm</name><affiliation wicri:level="4"><nlm:aff id="aff2">University of Hohenheim, Stuttgart, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>University of Hohenheim, Stuttgart</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Stuttgart</region><settlement type="city">Stuttgart</settlement></placeName><orgName type="university">Université de Hohenheim</orgName></affiliation></author><author><name sortKey="Fasanella, Antonio" sort="Fasanella, Antonio" uniqKey="Fasanella A" first="Antonio" last="Fasanella">Antonio Fasanella</name><affiliation wicri:level="1"><nlm:aff id="aff3">Istituto Zooprofilattico Sperimentale of Puglia and Basilicata, Foggia, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Istituto Zooprofilattico Sperimentale of Puglia and Basilicata, Foggia</wicri:regionArea><wicri:noRegion>Foggia</wicri:noRegion></affiliation></author><author><name sortKey="Garofolo, Giuliano" sort="Garofolo, Giuliano" uniqKey="Garofolo G" first="Giuliano" last="Garofolo">Giuliano Garofolo</name><affiliation wicri:level="1"><nlm:aff id="aff3">Istituto Zooprofilattico Sperimentale of Puglia and Basilicata, Foggia, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Istituto Zooprofilattico Sperimentale of Puglia and Basilicata, Foggia</wicri:regionArea><wicri:noRegion>Foggia</wicri:noRegion></affiliation></author><author><name sortKey="Golinski, Robert" sort="Golinski, Robert" uniqKey="Golinski R" first="Robert" last="Golinski">Robert Golinski</name><affiliation wicri:level="3"><nlm:aff id="aff4">Department of Immunology, Max Planck Institute for Infection Biology, Charitéplatz 1, D-10117 Berlin, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Immunology, Max Planck Institute for Infection Biology, Charitéplatz 1, D-10117 Berlin</wicri:regionArea><placeName><region type="land" nuts="3">Berlin</region><settlement type="city">Berlin</settlement></placeName></affiliation></author><author><name sortKey="Goossens, Pierre L" sort="Goossens, Pierre L" uniqKey="Goossens P" first="Pierre L." last="Goossens">Pierre L. 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E." last="Kaufmann">Stefan H. E. Kaufmann</name><affiliation wicri:level="3"><nlm:aff id="aff4">Department of Immunology, Max Planck Institute for Infection Biology, Charitéplatz 1, D-10117 Berlin, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Immunology, Max Planck Institute for Infection Biology, Charitéplatz 1, D-10117 Berlin</wicri:regionArea><placeName><region type="land" nuts="3">Berlin</region><settlement type="city">Berlin</settlement></placeName></affiliation></author></analytic><series><title level="j">International Journal of Medical Microbiology</title><idno type="ISSN">1438-4221</idno><idno type="eISSN">1618-0607</idno><imprint><date when="2008">2008</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Anthrax Euronet, a Coordination Action of the EU 6th Framework Programme, was designed to strengthen networking activities between anthrax research groups in Europe and to harmonise protocols for testing anthrax vaccines and therapeutics. Inevitably, the project also addressed aspects of the current political issues of biosecurity and dual-use research, i.e. research into agents of important diseases of man, livestock or agriculture that could be used as agents of bioterrorism. This review provides a comprehensive overview of the biology of <italic>Bacillus anthracis</italic>, of the pathogenesis, epidemiology and diagnosis of anthrax, as well as vaccine and therapeutic intervention strategies. The proposed requirement for a code of conduct for working with dual-use agents such as the anthrax bacillus is also discussed.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Abrami, L" uniqKey="Abrami L">L. Abrami</name></author><author><name sortKey="Reig, N" uniqKey="Reig N">N. 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Mock</name></author><author><name sortKey="Montecucco, C" uniqKey="Montecucco C">C. Montecucco</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wang, W" uniqKey="Wang W">W. Wang</name></author><author><name sortKey="Mulakala, C" uniqKey="Mulakala C">C. Mulakala</name></author><author><name sortKey="Ward, S C" uniqKey="Ward S">S.C. Ward</name></author><author><name sortKey="Jung, G" uniqKey="Jung G">G. Jung</name></author><author><name sortKey="Luong, H" uniqKey="Luong H">H. Luong</name></author><author><name sortKey="Pham, D" uniqKey="Pham D">D. Pham</name></author><author><name sortKey="Waring, A J" uniqKey="Waring A">A.J. Waring</name></author><author><name sortKey="Kaznessis, Y" uniqKey="Kaznessis Y">Y. Kaznessis</name></author><author><name sortKey="Lu, W" uniqKey="Lu W">W. Lu</name></author><author><name sortKey="Bradley, K A" uniqKey="Bradley K">K.A. Bradley</name></author><author><name sortKey="Lehrer, R I" uniqKey="Lehrer R">R.I. Lehrer</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wei, W" uniqKey="Wei W">W. Wei</name></author><author><name sortKey="Lu, Q" uniqKey="Lu Q">Q. Lu</name></author><author><name sortKey="Chaudry, G J" uniqKey="Chaudry G">G.J. Chaudry</name></author><author><name sortKey="Leppla, S H" uniqKey="Leppla S">S.H. Leppla</name></author><author><name sortKey="Cohen, S N" uniqKey="Cohen S">S.N. Cohen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Welkos, S L" uniqKey="Welkos S">S.L. Welkos</name></author><author><name sortKey="Friedlander, A M" uniqKey="Friedlander A">A.M. Friedlander</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Witkowski, J A" uniqKey="Witkowski J">J.A. Witkowski</name></author><author><name sortKey="Parish, L C" uniqKey="Parish L">L.C. Parish</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Young, J" uniqKey="Young J">J. Young</name></author><author><name sortKey="Bromberg White, J" uniqKey="Bromberg White J">J. Bromberg-White</name></author><author><name sortKey="Zylstra, C" uniqKey="Zylstra C">C. Zylstra</name></author><author><name sortKey="Church, J" uniqKey="Church J">J. Church</name></author><author><name sortKey="Boguslawski, E" uniqKey="Boguslawski E">E. Boguslawski</name></author><author><name sortKey="Resau, J" uniqKey="Resau J">J. Resau</name></author><author><name sortKey="Williams, B" uniqKey="Williams B">B. Williams</name></author><author><name sortKey="Duesbery, N" uniqKey="Duesbery N">N. Duesbery</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Allemagne</li><li>France</li><li>Italie</li><li>Royaume-Uni</li></country><region><li>Bade-Wurtemberg</li><li>Berlin</li><li>District de Stuttgart</li><li>Île-de-France</li></region><settlement><li>Berlin</li><li>Paris</li><li>Stuttgart</li></settlement><orgName><li>Université de Hohenheim</li></orgName></list><tree><country name="Royaume-Uni"><noRegion><name sortKey="Hudson, Michael J" sort="Hudson, Michael J" uniqKey="Hudson M" first="Michael J." last="Hudson">Michael J. Hudson</name></noRegion><name sortKey="Hallis, Bassam" sort="Hallis, Bassam" uniqKey="Hallis B" first="Bassam" last="Hallis">Bassam Hallis</name><name sortKey="King, Annemarie" sort="King, Annemarie" uniqKey="King A" first="Annemarie" last="King">Annemarie King</name></country><country name="Allemagne"><region name="Bade-Wurtemberg"><name sortKey="Beyer, Wolfgang" sort="Beyer, Wolfgang" uniqKey="Beyer W" first="Wolfgang" last="Beyer">Wolfgang Beyer</name></region><name sortKey="Bohm, Reinhard" sort="Bohm, Reinhard" uniqKey="Bohm R" first="Reinhard" last="Böhm">Reinhard Böhm</name><name sortKey="Golinski, Robert" sort="Golinski, Robert" uniqKey="Golinski R" first="Robert" last="Golinski">Robert Golinski</name><name sortKey="Hahn, Ulrike" sort="Hahn, Ulrike" uniqKey="Hahn U" first="Ulrike" last="Hahn">Ulrike Hahn</name><name sortKey="Kaufmann, Stefan H E" sort="Kaufmann, Stefan H E" uniqKey="Kaufmann S" first="Stefan H. E." last="Kaufmann">Stefan H. E. Kaufmann</name><name sortKey="Ozin, Amanda" sort="Ozin, Amanda" uniqKey="Ozin A" first="Amanda" last="Ozin">Amanda Ozin</name></country><country name="Italie"><noRegion><name sortKey="Fasanella, Antonio" sort="Fasanella, Antonio" uniqKey="Fasanella A" first="Antonio" last="Fasanella">Antonio Fasanella</name></noRegion><name sortKey="Garofolo, Giuliano" sort="Garofolo, Giuliano" uniqKey="Garofolo G" first="Giuliano" last="Garofolo">Giuliano Garofolo</name><name sortKey="Montecucco, Cesare" sort="Montecucco, Cesare" uniqKey="Montecucco C" first="Cesare" last="Montecucco">Cesare Montecucco</name><name sortKey="Tonello, Fiorella" sort="Tonello, Fiorella" uniqKey="Tonello F" first="Fiorella" last="Tonello">Fiorella Tonello</name></country><country name="France"><region name="Île-de-France"><name sortKey="Goossens, Pierre L" sort="Goossens, Pierre L" uniqKey="Goossens P" first="Pierre L." last="Goossens">Pierre L. Goossens</name></region><name sortKey="Mock, Michele" sort="Mock, Michele" uniqKey="Mock M" first="Michèle" last="Mock">Michèle Mock</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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